Dave Coulier, beloved by fans as the funny and warm-hearted Joey Gladstone on “Full House,” has opened up about facing one of the toughest challenges of his life. However, Dave remains hopeful, drawing strength from his family and close-knit support network.

Central to his support system is his wife, Melissa, whose presence has been a source of comfort and encouragement. Together, they are facing this journey head-on, showing the strength of their bond and their determination to overcome whatever lies ahead.

Dave’s battle began with what seemed like a minor inconvenience—a lingering cold. However, as the symptoms persisted, he noticed a golf ball-sized lump in his groin. Initially, he didn’t think much of it, but the lump grew rapidly, prompting a visit to the doctor.

Though early tests showed promising results, doctors were concerned about the speed of the lump’s growth. Further examinations revealed the true extent of the issue: Stage 3 B-cell lymphoma, a type of non-Hodgkin lymphoma that affects the blood.

The sudden shift from minor symptoms to a serious diagnosis was overwhelming. It left the actor in disbelief but determined to face the challenge head-on.

As Dave battles his cancer, he’s found massive support in his wife, Melissa Coulier. A producer and an entrepreneur, Melissa has stepped into the role of caregiver with determination and expertise.

Beyond her creative talents, Melissa is also a fitness trainer and wellness advocate, with an admirable relationship with Dave’s son, Luc, born from his previous marriage.

“So proud to be a step-parent to this guy!” Melissa once captioned a photo of them, showcasing the genuine affection she has for Luc. Their strong connection has made Melissa’s support even more impactful, as the family navigates this difficult time together.

Before becoming each other’s biggest support system, Dave and Melissa shared a strong friendship that began nearly a decade before they tied the knot.

Their story started in Montana during a guys’ trip. Dave was sitting at a booth telling a story when he accidentally tripped Melissa as she walked by. Instead of being upset, she laughed it off, and the two hit it off instantly, marking the beginning of a close friendship.

By June 2014, the couple announced their engagement, and Dave expressed his joy, “I get to marry my best friend.” He also gushed about feeling like “the luckiest man on the planet.”

The wedding took place on July 2, 2014, at O’Hair Ranch Lodge in Paradise Valley, Montana. The event was intimate and low-key, with Melissa handling most of the planning herself.

The couple exchanged non-traditional rings, with Dave opting for a black titanium band and Melissa wearing a piece from XIV Karats. They also chose to skip traditional wedding vows, instead keeping the ceremony short and sweet.

With a laugh, she responded, “Yeah, let’s have a beer!” It was a fitting moment for the laid-back pair whose easygoing friendship had been at the core of their relationship from the start. This bond has helped them face life’s toughest challenges together over the years.

Melissa has proven to be more than just a loving wife and friend. She’s been an unshakeable pillar of strength for Dave during his most challenging times. Years back, Dave faced a battle with alcohol addiction.

“The mental and physical withdrawal were big challenges for me,” he shared, “but I was supported by @melissacoulier and friends who had already made the journey.”

This is mirrored in how she immediately stepped into action upon learning his cancer diagnosis. Dave described how she “organized [his] entire life,” handling everything from medical appointments and pills to nutrition plans.

Dave’s friends and former “Full House” co-stars have also acknowledged Melissa’s vital role in his care. They’ve expressed their admiration, telling him, “You’re in great hands with Mel.”

While the diagnosis was a shock, having Melissa by his side gave him the strength and confidence to face the road ahead. Her efforts have gone beyond typical caregiving, blending her expertise in wellness with a deep commitment to his well-being.

While traditional chemotherapy has been a central part of Dave’s medical plan, the couple decided to incorporate a holistic strategy, drawing on Melissa’s background in wellness. Her expertise has played a crucial role in creating a comprehensive plan that focuses on both body and mind.

Infrared saunas, breathwork, and massages have become regular parts of his routine, aimed at alleviating discomfort and promoting relaxation during treatment. Commending her husband’s courage as he battles his illness, Melissa shared in a social media post, “Dave’s resilience inspires me every day.”

Despite the difficulties of his health battle, Dave has found a bright spot on the horizon — the joy of becoming a grandfather for the first time. The news came at a pivotal moment for the actor, as his son, Luc, and daughter-in-law, Alex, are expecting their first child, a baby boy, due in March.

He can’t wait to introduce his grandson to his favorite pastimes, including hockey and airplanes. “There’s a lot to look forward to,” Dave shared. The couple is already planning trips between Michigan and Los Angeles to visit the newest member of the family.

A cornerstone of their marriage has always been their shared sense of humor, which has helped them through tough times. In a past interview, Dave shared, “We laugh a lot. Through all the ups and downs, we’ve always found a way to laugh and see the silver lining.”